The estimated 2008 population of San Francisco was 808,976. With over 16,000 people per square mile, San Francisco is the second-most densely populated major American city. San Francisco is the traditional focal point of the San Francisco Bay Area and forms part of the San Francisco-Oakland-Fremont Metropolitan Statistical Area and the greater San Jose-San Francisco-Oakland Combined Statistical Area (CSA) whose population is over seven million, making it the fifth largest in the United States as of the 2000 Census.
Like many larger U.S. cities, San Francisco is a minority-majority city, as non-Hispanic whites comprise less than half of the population. As of 2007, the Census Bureau estimated that 45.0 percent of the population was non-Hispanic white. Asian Americans make up 33.1% of the population; Chinese Americans constitute the largest single ethnic group in San Francisco at about a fifth of the population. Hispanics of any race make up 14.0% of the population. San Francisco's African American population has declined in recent decades, from 13.4 percent of the city in 1970 to 7.3 percent of the population in 2007. The current percentage of African Americans in San Francisco is similar to that of the state of California.
Native San Franciscans form a relatively small percentage of the city's population: only 37.4 percent of its residents were born in California, while 26.9 percent were born in a different U.S. state. More than a third of city residents (35.7 percent) were born outside the United States.
According to the 2005 American Community Survey, San Francisco has the highest percentage of gay and lesbian individuals of any of the 50 largest U.S cities, at 15.4%. San Francisco also has the highest percentage of same-sex households of any American county, with the Bay Area having a higher concentration than any other metropolitan area.
The San Francisco median household income in 2007 was $65,519, with the median family income at $81,136. Following a national trend, an out-migration of middle class families is contributing to widening income disparity and has left the city with a lower proportion of children, 14.5 percent, than any other large American city.
The city's poverty rate, at 7.7 percent, is lower than the national average and among the lowest for cities ranked by the U.S. Census Bureau.
Homelessness has been a chronic and controversial problem for San Francisco since the early 1980s. The city is believed to have the highest number of homeless inhabitants per capita of any major U.S. city.
San Francisco's rates of violent and property crime, reported for 2006 as 875 and 4,958 incidents per 100,000 residents respectively, are higher than the national average.
Because of its unique geography—making beltways somewhat impractical—and the results of the freeway revolts of the late 1950s, San Francisco is one of the few American cities that has opted for European-style arterial thoroughfares instead of a large network of freeways. This trend continued following the 1989 Loma Prieta Earthquake, when city leaders decided to demolish the Embarcadero Freeway, and voters approved demolition of a portion of the Central Freeway, converting them into street-level boulevards.
Interstate 80 begins at the approach to the Bay Bridge and is the only direct automobile link to the East Bay. U.S. Route 101 extends Interstate 80 to the south along the San Francisco Bay toward Silicon Valley. Northbound, 101 uses arterial streets Van Ness Avenue and Lombard Street to the Golden Gate Bridge, the only direct road access from San Francisco to Marin County and points north. Highway 1 also enters San Francisco at the Golden Gate Bridge, but diverts away from 101, bisecting the west side of the city as the 19th Avenue arterial thoroughfare, and joining with Interstate 280 at the city's southern border. Interstate 280 continues this route along the central portion of the Peninsula south to San Jose. Northbound, 280 turns north and east and terminates in the South of Market area. State Route 35, which traverses the majority of the Peninsula along the ridge of the Santa Cruz Mountains, enters the city from the south as Skyline Boulevard, following city streets until it terminates at its intersection with Highway 1. State Route 82 enters San Francisco from the south as Mission Street, following the path of the historic El Camino Real and terminating shortly thereafter at its junction with 280. The cross-country Lincoln Highway's western terminus is in Lincoln Park. Major east–west thoroughfares include Geary Boulevard, the Lincoln Way/Fell Street corridor, and Market Street/Portola Drive.
Cycling is a popular mode of transportation in San Francisco, with about 40,000 residents commuting to work regularly by bicycle.
Many people in San Francisco use public transportation, nearly a third of commuters in 2005. Public transit solely within the city of San Francisco is provided predominantly by the San Francisco Municipal Railway (Muni). The city-owned system operates both a combined light rail/subway system (the Muni Metro) and a bus network that includes trolleybuses, standard diesel motorcoaches and diesel hybrid buses. The Metro streetcars run on surface streets in outlying neighborhoods but underground in the downtown area. Additionally, Muni runs the highly visible F Market historic streetcar line, which runs on surface streets from Castro Street to Fisherman's Wharf (through Market Street), and the iconic San Francisco cable car system, which has been designated as a National Historic Landmark.
Commuter rail is provided by two complementary agencies. Bay Area Rapid Transit (BART) is the regional rapid transit system which connects San Francisco with the East Bay through the Transbay Tube. The line runs under Market Street to Civic Center, where it turns south to the Mission District, the southern part of the city, and through northern San Mateo County, to the San Francisco International Airport, and Millbrae. The Caltrain rail system runs from San Francisco along the Peninsula down to San Jose. The line dates from 1863, and for many years was operated by Southern Pacific.
The Transbay Terminal serves as the terminus for long-range bus service (such as Greyhound) and as a hub for regional bus systems AC Transit (Alameda County), SamTrans (San Mateo County), and Golden Gate Transit (Marin and Sonoma Counties). Amtrak also runs a shuttle bus from San Francisco to its rail station in Emeryville.
A small fleet of commuter and tourist ferries operate from the Ferry Building and Pier 39 to points in Marin County, Oakland, and north to Vallejo in Solano County.
San Francisco International Airport (SFO), though located 13 miles (21 km) south of the city in San Mateo County, is under the jurisdiction of the City and County of San Francisco. SFO is primarily adjacent to the cities of Millbrae and San Bruno, but also borders the most southern part of the city of South San Francisco. SFO is a hub for United Airlines, its largest tenant, and the decision by Virgin America to base its operations out of SFO reversed the trend of low-cost carriers opting to bypass SFO for Oakland and San Jose. SFO is an international gateway, with the largest international terminal in North America. The airport is built on a landfill extension into the San Francisco Bay. During the economic boom of the late 1990s, when traffic saturation led to frequent delays, it became difficult to respond to calls to relieve the pressure by constructing an additional runway as that would have required additional landfill. Such calls subsided in the early 2000s as traffic declined, and, in 2006, SFO was the 14th busiest airport in the U.S. and 26th busiest in the world, handling 33.5 million passengers.
The Port of San Francisco was once the largest and busiest seaport on the West Coast. It featured rows of piers perpendicular to the shore, where cargo from the moored ships was handled by cranes and manual labor and transported to nearby warehouses. The port handled cargo to and from trans-Pacific and Atlantic destinations, and was the West Coast center of the lumber trade. The 1934 West Coast Longshore Strike, an important episode in the history of the American labor movement, brought the port to a standstill. The advent of container shipping made pier-based ports obsolete, and most commercial berths moved to the Port of Oakland. A few active berths specializing in break bulk cargo remain alongside the Islais Creek Channel.
Many piers remained derelict for years until the demolition of the Embarcadero Freeway reopened the downtown waterfront, allowing for redevelopment. The centerpiece of the port, the Ferry Building, while still receiving commuter ferry traffic, has been restored and redeveloped as a gourmet marketplace. The port's other activities now focus on developing waterside assets to support recreation and tourism.