Located on the banks of the Tombigbee River, Aberdeen was one of the busiest Mississippi ports of the nineteenth century. Cotton was heavily traded in town, and for a time Aberdeen was Mississippi's second largest city. Today Aberdeen retains many historic structures from this period, with over 200 buildings on the National Register of Historic Places. In the spring of each year, Aberdeen hosts pilgrimages to its historic antebellum homes. The most prominent of these antebellum homes is The Magnolias, which was built in 1850.
Located just outside the city, Aberdeen Lock and Dam forms Aberdeen Lake, a popular recreational area. Aberdeen Lock and Dam is part of the Tennessee-Tombigbee waterway system.
As of the census of 2000, there were 6,415 people, 2,398 households, and 1,661 families residing in the city. The population density was 598.8 people per square mile (231.3/km²). There were 2,730 housing units at an average density of 254.8/sq mi (98.4/km²). The racial makeup of the city was 60.20% African American, 38.78% White, 0.09% Native American, 0.39% Asian, 0.05% Pacific Islander, 0.06% from other races, and 0.42% from two or more races. Hispanic or Latino of any race were 0.56% of the population.
There were 2,398 households out of which 36.3% had children under the age of 18 living with them, 35.8% were married couples living together, 29.9% had a female householder with no husband present, and 30.7% were non-families. 27.6% of all households were made up of individuals and 13.6% had someone living alone who was 65 years of age or older. The average household size was 2.58 and the average family size was 3.14.
In the city the population was spread out with 29.8% under the age of 18, 8.8% from 18 to 24, 25.7% from 25 to 44, 19.8% from 45 to 64, and 15.9% who were 65 years of age or older. The median age was 34 years. For every 100 females there were 78.8 males. For every 100 females age 18 and over, there were 69.7 males.
The median income for a household in the city was $23,530, and the median income for a family was $27,611. Males had a median income of $27,857 versus $17,090 for females. The per capita income for the city was $11,584. About 26.3% of families and 29.6% of the population were below the poverty line, including 42.2% of those under age 18 and 26.7% of those age 65 or over.