The majority of the Village of Mineola is located in the Town of North Hempstead, with a slim portion of its southern edge within the Town of Hempstead. Old Country Road runs along the southern border of the village. The area serviced by the Mineola Post Office extends further south into the adjacent village of Garden City, New York, where the county seat of Nassau County is located. Offices of many Nassau agencies are located in both Mineola and Garden City.
As of the census of 2000, there were 19,234 people, 7,473 households, and 4,954 families residing in the village. The population density was 10,337.3 people per square mile (3,992.6/km²). There were 7,650 housing units at an average density of 4,111.5/sq mi (1,588.0/km²). The racial makeup of the village was 82.39% White, 1.03% African American, 0.29% Native American, 4.52% Asian, 0.04% Pacific Islander, 3.93% from other races, and 3.79% from two or more races. 13.03% of the population is Hispanic or Latino of any race.
There were 7,473 households out of which 27.0% had children under the age of 18 living with them, 53.2% were married couples living together, 9.3% had a female householder with no husband present, and 33.7% were non-families. 29.1% of all households were made up of individuals and 11.8% had someone living alone who was 65 years of age or older. The average household size was 2.57 and the average family size was 3.20.
In the village the population was spread out with 20.2% under the age of 18, 7.4% from 18 to 24, 34.1% from 25 to 44, 22.6% from 45 to 64, and 15.7% who were 65 years of age or older. The median age was 38 years. For every 100 females there were 92.5 males. For every 100 females age 18 and over, there were 89.6 males.
The median income for a household in the village was $60,706, and the median income for a family was $71,042. Males had a median income of $47,182 versus $37,057 for females. The per capita income for the village was $28,890. About 2.6% of families and 4.2% of the population were below the poverty line, including 3.5% of those under age 18 and 5.4% of those age 65 or over.