As of the census of 2000, there were 133,798 people, 52,539 households, and 32,258 families residing in the county. The population density was 205 people per square mile (79/km²). There were 58,408 housing units at an average density of 90 per square mile (35/km²). The racial makeup of the county was 62.08% White, 33.65% Black or African American, 0.27% Native American, 1.08% Asian, 0.04% Pacific Islander, 1.80% from other races, and 1.09% from two or more races. 3.15% of the population were Hispanic or Latino of any race.
There were 52,539 households out of which 29.90% had children under the age of 18 living with them, 43.40% were married couples living together, 14.40% had a female householder with no husband present, and 38.60% were non-families. 28.30% of all households were made up of individuals and 7.30% had someone living alone who was 65 years of age or older. The average household size was 2.43 and the average family size was 3.02.
In the county the population was spread out with 23.60% under the age of 18, 17.50% from 18 to 24, 29.90% from 25 to 44, 19.40% from 45 to 64, and 9.60% who were 65 years of age or older. The median age was 30 years. For every 100 females there were 90.20 males. For every 100 females age 18 and over, there were 86.40 males.
The median income for a household in the county was $32,868, and the median income for a family was $43,971. Males had a median income of $31,962 versus $25,290 for females. The per capita income for the county was $18,243. About 13.50% of families and 20.30% of the population were below the poverty line, including 21.60% of those under age 18 and 20.20% of those age 65 or over.
Pitt County is roughly 20 miles east of Interstate 95, which is a part of the largest state highway system in the nation. US Airways serves the Pitt-Greenville Airport daily with connecting flights to Charlotte Douglas International Airport. The airport and local officials are in discussion with United Airlines and its regional partner, Colgan Air, to provide 2 daily flights between PGV and Washington Dulles International Airport..
Major highways that run through the area include US 264, US 264 Bypass, US 258, NC 11, US 13, NC 33, NC 43, and NC 903.