As of the census of 2000, there were 4,779 people, 1,936 households, and 1,169 families residing in the city. The population density was 1,313.1 people per square mile (506.9/km²). There were 2,148 housing units at an average density of 590.2/sq mi (227.8/km²). The racial makeup of the city was 90.35% White, 0.36% African American, 5.46% Native American, 0.29% Asian, 0.08% Pacific Islander, 1.88% from other races, and 1.57% from two or more races. Hispanic or Latino of any race were 6.44% of the population.
There were 1,936 households out of which 30.5% had children under the age of 18 living with them, 44.4% were married couples living together, 12.3% had a female householder with no husband present, and 39.6% were non-families. 31.3% of all households were made up of individuals and 11.4% had someone living alone who was 65 years of age or older. The average household size was 2.43 and the average family size was 3.10.
In the city the population was spread out with 27.6% under the age of 18, 8.7% from 18 to 24, 28.5% from 25 to 44, 21.6% from 45 to 64, and 13.6% who were 65 years of age or older. The median age was 36 years. For every 100 females there were 95.1 males. For every 100 females age 18 and over, there were 92.7 males.
The median income for a household in the city was $32,620, and the median income for a family was $38,214. Males had a median income of $35,291 versus $21,339 for females. The per capita income for the city was $16,228. About 12.0% of families and 15.7% of the population were below the poverty line, including 19.1% of those under age 18 and 10.5% of those age 65 or over.
Prior to the construction of the railroad in 1883, Moab was a strategic place to cross the Colorado River.
A toll ferry service across the river ended when a permanent bridge was built in 1911. This bridge was replaced with the current bridge in 1955. The highway that uses this bridge has been renumbered multiple times and is presently numbered U.S. Route 191.
Moab gained freight railroad access in 1962, when a spur railroad line (now the Union Pacific Railroad's Cane Creek Subdivision) was built to service the Cane Creek potash mine. Moab has never had passenger rail service, although the California Zephyr has advertised service to Moab in the past via the stops at Thompson Springs (no longer a scheduled stop), Green River or Grand Junction, Colorado.
Moab currently does not have regular bus service, although charter busses and shuttle service to Salt Lake City or Grand Junction in Colorado are available.
Air service is available at Canyonlands Field.